F.A.Z. Wissen

FAZ Wissen Leben auf der Venus? Die Studie in "Nature Astronomy", Greaves et al. (2020), "Phosphine gas in the cloud decks of Venus" Supplements zur Venus-Studie ==================================== Editorial "The climate issue", erschienen in "Nature Astronomy" Australische Übersichtsstudie: "The imperative to reduce carbon emissions in astronomy" Kommentar zur CO2-Bilanz des MPIA in Heidelberg: "An astronomical institute’s perspective on meeting the challenges of the climate crisis" Kommentar zum Energieverbrauch astrophysikalischer Simulationen: "The ecological impact of high-performance computing in astrophysics" Vergleich der CO2-Bilanz einer Konferenz digital vs. analog: "The carbon footprint of large astronomy meetings" Weitere Studien, die nicht explizit zur Sprache kamen: Klimabilanz eines astronomischen Observatoriums: "Measuring carbon emissions at the Canada–France–Hawaii Telescope" Einfluss des Klimawandels auf astronomische Beobachtungen: "The impact of climate change on astronomical observations"

FAZ Wissen Die Paper für diesen Podcast: "A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants", B. Dearlove et al, PNAS, 2020 "Evolution of the COVID-19 vaccine development landscape", Tung Tanh Le et al, Nature, 2020

FAZ Wissen "Science"-Paper: Laurette Piani et al., 28.8.2020: "Earth's water may have been inherited from material similar to enstatite chondrite meteorites" "Science"-Kommentar: Anne H. Peslier, 28.8.2020: "The origins of water" Biographischer Exkurs -- Schneelinien und was man sonst noch daraus lernen kann ;-): Anderl et al. (2016): "Probing the CO and methanol snow lines in young protostars. Results from the CALYPSO IRAM-PdBI survey", A&A Glosse: "Woher kommt all das Wasser?"

FAZ Wissen Die Paper für diesen Podcast: Ching-Yao Lai et al, Nature, 2020: Vulnerability of Antarctica’s ice shelves to meltwater-driven fracture Thomas Slater et al, The Cryosphere Discussions, 2020 Review Article: Earth’s ice imbalance Daisuke Hirano et al, Nature Communications, 2020 Strong ice-ocean interaction beneath Shirase Glacier Tongue in East Antarctica Susheel Adusumilli et al, Nature Geoscience, 2020, Interannual variations in meltwater input to the Southern Ocean from Antarctic ice shelves

FAZ Wissen Die Paper für unseren Podcast: Jerome Hadjadj et al, Science (2020), "Immune analysis in fifty patients uncovers 'hallmark' of severe COVID-19" Anna Aschenbrenner et al, medRxiv (2020), "Disease severity-specific neutrophil signatures in blood 1 transcriptomes stratify COVID-19 patients" Dimitris Bertsimas et al, medRxiv (2020), "COVID-19 Mortality Risk Assessment: An International Multi-Center Study"

FAZ Wissen Euromomo-Zusammenfassung: "Excess all-cause mortality during the COVID-19 pandemic in Europe - preliminary pooled estimates from the EuroMOMO network, March to April 2020", 2.7.2020 Jama-Editorial zur Mortalität und Morbidität: "Mortality and Morbidity - The measure of a Pandemic"; 1.7.2020 S. Woolf et al. "Excess Deaths From Covid-19 and Other Causes, March-April 2020", Jama 1.7.2020 D. Weinberger et al. "Estimation of Excess Deaths Associated With the Covid-19 Pandemic in the United States, March to May 2020", Jama 1.7.2020

FAZ Wissen Einige Paper zu unserem Podcast: Diabetes durch Sars-CoV-2-Infektion: F. Rubino et al, NEJM (2020), "New-Onset Diabetes in Covid-19" J. Li et al, Diabetes, Obesity and Metabolism (2020), COVID ‐19 infection may cause ketosis and ketoacidosis Noel Pratheepan Somasundaram et al, The Journal of the Endocrine Society (2020), The Impact of SARS-Cov-2 Virus Infection on the Endocrine System Nieren-Komplikationen: J. Hirsch et al, Clinical Investigation (2020), Acute kidney injury in patients hospitalizedwith COVID-19 Inflammatorisches Syndrom bei Kindern: Michael Levin, NEJM (2020), Childhood Multisystem Inflammatory Syndrome — A New Challenge in the Pandemic

FAZ Wissen Zu schwer für einen Neutronenstern, zu leicht für ein Schwarzes Loch - das neue Ligo-Paper: GW190814: Gravitational Waves from the Coalescence of a 23 Solar Mass Black Hole with a 2.6 Solar Mass Compact Object Quantenkorrelationen im Ligo-Experiment: Quantum correlations between light and the kilogram-mass mirrors of LIGO

F.A.Z. Wissen Die Paper für dieses Podcast-Folge: Xin Long et al (2020, Nature Medicine, "Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections" Mary Marovich et al (2020), Jama, "Monoclonal Antibodies for Prevention and Treatment of COVID-19" Zum Thema auch interessant u.a.: Davide F. Robbian et al, (20209; Nature "Convergent antibody responses to SARS-CoV-2 in convalescent individuals" Thomas Rogers et al (2020), Science "Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model" Thomas F. Rogers

FAZ Wissen Die im Podcast besprochenen Paper: Lucy van Dorp, Francois Balloux et al. (2020), Infection, Genetics and "Evolution, Emergence of genomic diversity and recurrent mutations in SARS-CoV-2" Nsoesie Elaine Okanyene, Benjamin Rader, Yiyao L. Barnoon,Lauren Goodwin, and John S. Brownstein. (2020) Preprint, Harvard Library DASH "An Analysis of hospital traffic and searchengine data in Wuhan China indicates early disease activity in the Fall of 2019"

FAZ Wissen Studie des Kepler-160 Systems: René Heller et al. 2020, "Transit least-squares survey - III. A 1.9 R_Earth transit candidate in the habitable zone of Kepler-160 and a nontransiting planet characterized by transit-timing variations", A&A Studie zum Einfluss von Staub in den Atmosphären von Exoplaneten: Ian Boutle et al. 2020, "Mineral dust increases the habitability of terrestrial planets but confounds biomarker detection", Nature Communications

FAZ Wissen Unsere Paper aus dem Podcast: D.R. Boulware et al, (2020) New England Journal of Medicine, "A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19" Mandeep R.Mehra et al, (2020) Lancet "Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis" Michael Takla et al, (2020) medRxiv "Chloroquine, hydroxychloroquine, and COVID-19: systematic review and narrative synthesis of efficacy and safety"

FAZ Wissen Unsere im Podcast besprochenen Paper: J.-L. Casanova & Covid Human Genetic Effort et al, Cell (2020): "A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection" Zur Rolle von "Schlüssel"-Bausteinen: C. Bhattacharyya et al, bioRxiv (2020) "Global Spread of SARS-CoV-2 Subtype with Spike Protein Mutation D614G is Shaped by Human Genomic Variations that Regulate Expression of TMPRSS2and MX1 Genes" Außerdem zur Rolle von ACE2 und zur Frage der Covid-19-Anfälligkeit von Männern: I. Sama et al, European heart Journal (2020) "Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors" Britische Studie zu klinischen Risikofaktoren: The OpenSAFELY Collaborative et al., medRxiv (2020) "The factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients"

FAZ Wissen T. Britton et al., 8.5.2020, "The disease-induced herd immunity level for Covid-19 is substantially lower than the classical herd immunity level" - schwedische Modellstudie zur Änderung der Herdenimmunität in heterogenen Gruppen M. G. M. Gomes et al., 2.5.2020, "Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold" - andere Modellstudie mit abweichendem Ansatz zur Repräsentation von Heterogenität. Annahme: Diejenigen mit der größten Ansteckungsgefahr stecken auch die meisten an. Heinsberg Studie, H. Streeck et al. (15 Prozent der Getesteten mit Antikörpern) Österreich: repräsentative Stichprobe in 27 Risikogemeinden liefert knapp 5% in der Vergangenheit Infizierte Schwedische Modellstudie zum Anteil der Infizierten in der Region Stockholm, die zum 1. Mai auf 26 Prozent geschätzt wird.

FAZ Wissen Unsere Paper aus bisher noch ungeprüften Originalpublikationen: Korber B. et al, 2020, bioRxiv, "Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2" https://www.biorxiv.org/content/10.1101/2020.04.29.069054v1 Lanjuan Li et al, 2020, MedRxiv, "Patient-derived mutations impact pathogenicity of SARS-CoV-2" https://www.medrxiv.org/content/10.1101/2020.04.14.20060160v2 Außerdem ein Überblick in unserem FAZ-Artikel "Das verwunschene Virus", auch online auf FAZ.NET mit dem Titel: "Wohin driftet die Pandemie?" https://www.faz.net/aktuell/wissen/medizin-ernaehrung/mutierte-gene-von-sars-cov-2-wohin-driftet-die-corona-pandemie-16754535.html?premium

FAZ Wissen Studie des Effekts der chinesischen Reiseeinschränkungen: Chinazzi et al. , 24. 4. 2020: “The effect of travel restrictions on the spread of the 2019 novel coronarivus (Covid-19) outbreak”, Science 368, 395: Modell-Studie zu den Effekte verschiedener Maßnahmen auf die Ausbreitung einer Pandemie in Großbritannien und den Vereinigten Staaten: Ferguson et al. 2006: “Strategies for mitigating an influenza pandemic.“, Nature 442: Zusätzliche Informationen über die Funktionsweisen und Ergebnisse des Modells: Ferguson et al. 2006: “Supplements: Strategies for mitigating an influenza pandemic.“, Nature 442:

FAZ Wissen Die Liste der behandelten Paper und wertvolle Zusatzinformationen: Science, 2020, M. Wadman et al.: "How does Coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes" https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes Nature Immunology Review, 2020, Xuetao Cao: "Covid-19: Immunopathology and its implications for therapy" https://www.nature.com/articles/s41577-020-0308-3 Zum Thema Zytokin-Sturm: Journal of Microbioal Agents, 2020: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118634/pdf/main.pdf

FAZ Wissen Webpage mit wöchentlichen Prognosen des Imperial College London Nouvellet et al. 2017: "A simple approach to measure transmissibility and forecast incidence"; Ebola-Studie, in der erklärt wird, wie aus den Daten die Reproduktionszahl ermittelt wird, um damit Vorhersagen zu ermöglichen Webpage mit Prognosen des IHME Murray et al. 2020: "Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilator-days and deaths by US state in the next 4 months"; Prognosemethode des IHME Expertenvergleich von Thomas McAndrew auf github Zusammenfassung der Expertenprognosen

FAZ Wissen **Hier die 5 ausgewählten Paper zum Thema: ** Respiratory virus shedding in exhaled breath and efficacy of face masks Nancy H.L. Leung et al, (2020) Nature Medicine Could SARS-CoV-2 be transmitted via speech droplets? [Philip Anfinrud et al (2020), MedRxiv] (https://www.medrxiv.org/content/10.1101/2020.04.02.20051177v1.full.pdf) The coronavirus pandemic and aerosols: Does COVID-19 transmit via expiratory particles? [Sima Asadi et al, (2020), Journal Aerosol Science and Technology ] (https://www.tandfonline.com/doi/full/10.1080/02786826.2020.1749229?scroll=top&needAccess=true) Transmission Potential of SARS-CoV-2 in viral Shedding Observed at the University of Nebraska Medical Center Joshua L Santarpia et al, (2020) MedRxiv Infection and Rapid Transmission of SARS-CoV-2 in Ferrets [Young-Il Kim et al, (2020) Cell Host & Microbes] (https://marlin-prod.literatumonline.com/pb-assets/journals/research/cell-host-microbe/PDFs/chom_2285_preproof.pdf)

FAZ Wissen Wissenschaftsphilosophischer Artikel "Model Evaluation: An Adequacy-for-Purpose View" von Wendy Parker Historisches SIR-Modell "A Contribution to the Mathematical Theory of Epidemics" von Kermack & McKendrick (1927) RKI-Modellierung "Modellierung von Beispielszenarien der Sars-CoV-2-Epidemie in Deutschland" von M. an der Heiden & U. Buchholz, 20. März 2020 Modellierungsstudie des Imperial College London zur Situation in den Vereinigten Staaten und Großbritannien "Impact of non-pharmaceutical interventions (NPIs) to reduce Covid-19 mortality and healthcare demand", 16. März 2020 Australische Validierungs-Studie: "Comparison of an Agent-based Model of Disease Propagation with the Generalised SIR Epidemic Model", 2009